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WEBAligos reports positive data from Phase IIa MASH treatment trial. In the trial, doses ranging from 0.5mg to 0.9mg of ALG-055009 led to notable median relative reductions in liver fat. News.
Gilead’s lenacapavir: HIV prospects strongest in long-acting …
WEBAug 25, 2021 · Gilead’s lenacapavir will find its strongest niche as a long-acting HIV combination treatment, experts said. Manasi Vaidya August 25, 2021. Gilead announced a collaboration with Merck in March to study lenacapavir with islatravir, a nucleoside reverse transcriptase translocation inhibitor (NRTTI), which is also a new drug class in HIV.
Obesity: Six trials to watch over the next 12 months
WEBJun 30, 2023 · According to a report by GlobalData, the market for obesity drugs is predicted to be worth $37.1bn in 2031. GlobalData is a parent company of the Clinical Trials Arena. As more trials take place globally, not only will this help to provide a wider range of treatments for patients but will also assist the unmet need of lack of supply.
Pfizer and BioNTech’s Covid-19/flu ... - Clinical Trials Arena
WEBAug 16, 2024 · Pfizer and BioNTech have announced that a Phase III trial studying their investigational combination mRNA vaccine for the treatment of influenza and Covid-19 has failed to meet one of its two primary endpoints.. While the vaccine demonstrated a trend of higher responses in neutralising the influenza A strain compared to a licensed influenza vaccine, it failed to demonstrate non-inferiority ...
Viridian Therapeutics' stock jumps after Phase III trial met all …
WEBSep 11, 2024 · The news saw the Massachusetts-based company’s stock price rise by 32% on 10 September, having closed at $14.19 on 9 September and $18.75 on 10 September. The trial met the primary and all secondary endpoints at 15 weeks after five infusions of veligrotug, showing highly statistically significant improvements in …
Top Ongoing mRNA Herpes Vaccine Trials - Clinical Trials Arena
WEBFeb 2, 2023 · Pfizer and Moderna eye seasonal influenza. The two largest mRNA vaccine trials with readouts in 2023 are for seasonal influenza. First up, Moderna’s 6,102-patient, Phase III trial of mRNA-1010 (NCT05415462) has immunogenicity data expected in Q1 2023. The trial is testing mRNA-1010 against an …
Jazz’s cannabidiol therapy flunks in Japanese Phase III trial
WEBAug 23, 2024 · Jazz Pharmaceuticals’ efforts to get its cannabidiol therapy approved in Japan have hit a snag after a Phase III trial in Japan evaluating the therapy failed to meet its primary endpoint.. The Phase III study evaluated the cannabidiol oral solution as an adjunct treatment for seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS) or tuberous sclerosis complex (TSC) in ...
News - Clinical Trials Arena
WEBSanofi’s eyes approval after MS therapy slows disease progression by 31%. Sanofi is eyeing up global regulatory approval for tolebrutinib after releasing positive Phase III data in non-relapsing secondary progressive multiple…. Phalguni Deswal.
ProKidney drops Phase III CKD study to focus on US market and …
WEBSep 4, 2024 · The trials enrol patients with type 2 diabetes and chronic kidney disease (CKD). CKD can be a complication of type 2 diabetes. Credit: NTshutterth via Shutterstock. ProKidney is dropping an ex-US Phase III study for its chronic kidney disease (CKD) cell therapy rilparencel, following discussions ...
New biomarker data supports NeuroSense’s ALS drug
WEBAug 2, 2024 · NeuroSense has shared new biomarker data from the Phase IIb PARADIGM study, showing that its amyotrophic lateral sclerosis (ALS) drug PrimeC (celecoxib and ciprofloxacin) regulated iron levels at 12 months. ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal …
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