I wouldn't do it, there's no justification for it. Some people might think there's a benefit in added lubrication of the valve train etc, but that's unlikely as diesel fuel does have some lubrication ...

A quick look around is all you need to think the two-stroke engine is dead. Exhaust smokers no longer brapp their way past outdoor cafés or over twisty mountain passes. You don't even see two-strokes ...