Microglia are known to play an important role in Alzheimer's disease, but exactly what they do has remained a mystery. Scientists in the Bart De Strooper Lab at the VIB-KU Leuven Center for Brain & ...

In this interview, Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s and other neurodegenerative diseases. Microglia are the primary immune ...

Scientists have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer's disease plaques and the LILRB4 receptor on microglia ...

Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...

Researchers have identified that microglia first help spread Alzheimer’s disease pathology across the brain and then activate to limit its neurodegenerative effects. Researchers from the VIB-KU Leuven ...

AB Science says a newly identified blood biomarker may help assess masitinib activity in its ongoing Phase 3 ALS clinical trial.

Mounting evidence links infections to a greater risk of dementia, and vaccination to neuroprotection. What underlies this relationship? In a preprint posted to Research Square on January 13, ...

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system. Microglia, the primary immune cells of the central ...