In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Students take samples of water and the microscopic creatures within at the Alviso Marina County Park. (Image by Erika Cardema) At the Alviso Marina County Park, reddish-brown water laps at the edge of ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

Single-cell barcoding and deep-sequencing technologies have conspired to enable highly scalable analysis of DNA or RNA with unprecedented resolution 1,2,3. Transcriptional states, regulatory networks ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...

Scaffolded DNA and RNA origami is a technique that allows scientists to build tiny, highly precise two- and three-dimensional ...

To assess the performance of the DNA conjugation scheme, we used a DNA amplicon from lambda phage (‘lambda DNA’) as a control analyte. The TCO-conjugated lambda DNA was added into MTz-functionalized ...

A new DNA sequencing technique that delivers faster and more accurate bacterial infection diagnoses could be implemented nationwide. The method, developed by the Medicines and Healthcare products ...