The endoplasmic reticulum is the protein-making factory within cells consisting of tightly stacked sheets of membrane studded with the molecules that make proteins. Now, researchers have refined a new ...

Myelinating cells, oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system produce an enormous amount of plasma membrane during the myelination process, making them particularly ...

A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...

Aberrant proteins are extremely harmful to cells. Such proteins can originate from mutations, unbalanced subunit synthesis, damaging conditions (for example, oxidation) and also as a side product of ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, has not ...

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered how a unique interaction between two cellular compartments, namely the endoplasmic reticulum (ER) and mitochondria, can act as ...

How these shapes arise, however, is largely a mystery. Harvard Medical School cell biologists have now cracked the code for part of the endoplasmic reticulum (ER), a protein - and fat-making organelle ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell’s main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

The body's cells change their shape to close gaps such as wounds – with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals ...