A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Natural enzymes have an exquisite ability to selectively and efficiently catalyze biochemical processes. Scientists have a great interest in harnessing that ability and putting these protein catalysts ...

Enzyme activity is commonly controlled by allostery, where ligand binding at one site alters the activities of distant sites. Classical explanations for multisubunit proteins involve conformational ...

Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

To be used industrially, enzymes usually need to undergo some surgery before they can become chemical workhorses. It may take a nip here, or a tuck there, to sculpt their active site into a shape that ...

Enzyme mechanisms of catalysis play many important roles in the functioning of a healthy body. An enzyme may exist as a multi-subunit complex or it may be associated with a cofactor such as adenosine ...

Scientists observed the characteristics of a single enzyme inside a nanopore. This revealed that the enzyme can exist in four different folded states, or conformers, that play an active role in the ...

As demand intensifies for "green chemistry" standards across the pharmaceutical and chemical industries, Creative Enzymes—a leading global enzyme technology service provider—today announced the ...

Enzymes are used extensively to produce complicated natural compounds and reducing the environmental footprint of chemical manufacturing, and hence it is important to know how they function. Enzymes ...

Unprecedented images of cancer genome-mutating enzymes acting on DNA provide vital clues into how the enzymes work to promote tumor evolution and drive poor disease outcomes, according to University ...

CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...