Long-acting antiviral medications are transforming HIV prevention and care, requiring only minimalistic dosing. But as the use of lenacapavir expands, scientists are probing a critical question: If ...

During a test drive, the mobile lab van uncovered a drug-resistant HIV strain that sprung up after the ongoing war with Russia started.

Pretreatment drug resistance (PDR) in patients with HIV varies by subtype, affecting antiretroviral therapy implementation and first-line treatment efficacy. In Hangzhou, 8.4% of newly diagnosed HIV ...

Effective control of the spread of HIV depends on using the right antiretroviral drugs. In 2019, the World Health Organization recommended using the integrase inhibitor, dolutegravir (DTG), in first- ...

HIV drug resistance (HIVDR) can emerge with use of antiretroviral (ARV) drugs for HIV treatment and prevention. The increasing prevalence of drug-resistant HIV strains poses a serious threat to the ...

Wesley Sundquist, PhD, Samuels Professor and chair of biochemistry at the University of Utah, laid the foundation for the development of a highly effective, long-lasting prophylactic against HIV, ...

The World Health Organization's (WHO) latest HIV Drug Resistance (HIVDR) Report tells us where drug resistance is growing and offers recommendations for countries to monitor and respond to the ...

A new study has overcome a long-standing challenge: how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease ...

A phase 3 clinical trial, led by Professor Chloe Orkin of Queen Mary University of London, has shown that a new, daily oral tablet that combines two current HIV treatment medications – bictegravir and ...

Just as life is ever-evolving, so is the HIV treatment landscape. Thanks to decades of therapeutic improvements, people with HIV are living longer, healthier lives, but additional treatment needs may ...

Study dissects HIV reservoir clones that persist on ART, revealing how CD8+ T cells and resistance pathways could be harnessed for future cure strategies.

Individuals with HIV who were resistant to all four antiretroviral drug classes experienced higher mortality than those who were not resistant, a difference primarily due to lower CD4 cell counts.