Sotatercept significantly reduces pulmonary vascular resistance in patients with CpcPH–HFpEF compared with placebo, according to a trial.

THE pulmonary circulation is of paramount importance in failure of the heart. The presence of dyspnea, orthopnea and hemoptysis and a diminution in vital capacity imply a profound change in the blood ...

Dr. Miranda Theodore (Medicine): A 28-year-old woman was transferred to the intensive care unit (ICU) of this hospital because of progressive respiratory failure. The patient had been in her usual ...

A pulmonary arteriovenous malformation is an abnormal connection between an artery and a vein within the lungs that allows deoxygenated venous blood to pass directly into the system circulation.

—Bradley Allen Maron, MD, of Brigham and Women’s Hospital and Harvard Medical School, discusses what we know—and especially what we don’t--about the epidemiology, pathophysiology, diagnosis, prognosis ...

Until now, there have been few therapeutic options for children with severely reduced heart pump function. Recently, surgical ...

Note that left and right refers to the side in the person's body, not how it is viewed on the page. The systemic circulation is under high pressure - it has to deliver blood to the extremities of the ...

The term ‘pulmonary’ refers to the lungs and ‘atresia’ means missing, so pulmonary atresia is a congenital heart defect in which the pulmonary valve of the infant is missing. The pulmonary valve ...

If you clench your hand into a fist, this is approximately the same size as your heart. It is located in the middle of the chest and slightly towards the left. The heart is a large muscular pump and ...

Pulmonary hypertension (PH) with left-sided heart disease is defined, according to the latest Venice classification, as a Group 2 PH, which includes left-sided ventricular or atrial disease, and ...