Ichthyosis vulgaris is a skin condition where the skin’s surface becomes dry, thick, and scaly. Most cases of ichthyosis vulgaris are hereditary and begin in childhood. In rare instances, adults can ...

Harlequin Ichthyosis (HI) is one of the rarest and most severe congenital skin disorders in the world. This disorder affects approximately 1 in 300,000 to 500,000 births. For decades, it was ...

In a cross-sectional study, the Ichthyosis Scoring System (ISS) demonstrated equal reliability in assessing scale and erythema severity across all skin types, with excellent interrater reliability for ...

Harlequin ichthyosis (HI) is the rarest and the most severe form of congenital ichthyosis. Inherited in an autosomal recessive manner, HI is primarily associated with mutations causing functional ...