MALDI remains a powerful tool for analyzing large biomolecules with minimal fragmentation. In this process, peptides or proteins are co-crystallized with a matrix on a metal plate. A laser pulse ...

As instruments grow faster, leaders say clinical impact will depend on trust, standards, data, and assays built for real ...

Can you provide an overview of your recent initiatives, particularly your spinout company and research institute, and how they relate to your academic work? We established the Parallel Squared ...

The sheer volume and complexity of data generated by modern mass spectrometry (MS)-based proteomics experiments necessitate robust, standardized bioinformatics infrastructure. This is particularly ...

Over the past several years, proteomics has seen a surge in interest among life scientists and the biopharma industry, akin to the previous rise of genomics. It is becoming more evident that ...

Mass spectrometry has evolved into a cornerstone of structural proteomics, offering rapid, sensitive and site-specific insights into protein architecture, interactions and dynamics. By coupling ...

Mass spectrometry–based proteomics encompasses a suite of analytical approaches designed to identify, characterise and quantify the full complement of proteins in biological samples. Central to these ...

Proteomics, which is generally defined as the characterization of the complete protein complement of a cell, tissue, or organism (a proteome), has moved to the forefront of "big science" now that the ...

Bruker Corporation today announced new advancements to enable Functional Proteomics 2.0 workflows on the timsOmni ™ mass spectrometer to enable disease researchers to move beyond canonical protein ...

When Matthew Padula was diagnosed with a rare bladder cancer in 2020, he knew there was a challenging road ahead of him. As a researcher at the University of Technology Sydney, his first instinct was ...

Protein biomarker discovery, validation and utilization require technologies that deliver proteome insights with breadth and depth. Liquid chromatography mass spectrometry (LC-MS), the gold-standard ...

Jianwei Shuai's team and Jiahuai Han's team at Xiamen University have developed a deep autoencoder-based data-independent acquisition data analysis software for protein mass spectrometry, which ...