Deep space is most likely going to be humanity’s final frontier, and space travel will undoubtedly become much more common in the future. However, space is a very hostile environment not only because ...

P-glycoprotein (P-gp) is a major membrane transporter associated with xenobiotic efflux that has been studied extensively in early drug development. Its level of expression influences the absorption ...

One of the well-established mechanisms of multidrug resistance (MDR) to chemotherapy in cancer patients is ATP binding cassette (ABC) transporter overexpression in cancer cell membrane, and as the ...

P-glycoprotein (P-gp) is one of several ABC transporters that can pump drugs out of tumor cells and thereby render chemotherapy ineffective. Overexpression of P-gp can give rise to multidrug ...