CycPeptMPDB, a novel database created by Tokyo Tech researchers, focuses on the membrane permeability of cyclic peptides and could accelerate the development of drugs based on these promising ...
Researchers at Nagoya University in Japan have developed a lipid nanoparticle that delivers mRNA to cells five times more effectively. By attaching a sulfur-containing ring structure—a cyclic ...
Scientists have developed stable orally available cyclic peptides with a much higher bioavailability than current ones, virtually creating a generation of drugs that can target previously untreatable ...
Cyclic peptides often exhibit low membrane permeability which can be significantly improved via amide-to-ester substitutions—as demonstrated by researchers from Tokyo Institute of Technology (Tokyo ...
Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way. Chemists can now produce an ...
A discovery could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance. A discovery made by scientists at King's College London could speed up efforts to produce ...
Small-molecule drugs have been instrumental in alleviating a gamut of ailments, from heart disease to the humble headache, but some experts now think we’ve exhausted the number of targets those drugs ...
TOKYO--(BUSINESS WIRE)--FUJIFILM Corporation announced today that it has developed an innovative screening methodology for cyclic peptides exhibiting high affinity toward membrane proteins 1. This new ...
CycPeptMPDB, a novel database—created by Tokyo Tech researchers—focused on the membrane permeability of cyclic peptides, could accelerate the development of drugs based on these promising compounds.
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