Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...
Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...
On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...
Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...
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Light-guided ‘optovolution’ creates proteins that flip states on cue
A peer-reviewed study published in Cell in March 2026 introduces “optovolution,” an in vivo directed-evolution system that uses light to breed proteins capable of switching between active and inactive ...
Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...
Fruit flies, mice, zebrafish, yeast and the tiny worm C. elegans are model organisms that have carried modern biology on ...
Since the COVID-19 pandemic, mRNA vaccines have gained attention as a next-generation pharmaceutical technology. mRNA therapeutics work by delivering genetic instructions that enable cells to produce ...
Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need for artificial intelligence (AI) models to effectively ...
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