Schematic representation of fitness landscapes. (A) Orange lines show maximum (dashed) and average (dotted) fitness of a population on a narrower peak (yellow circles), blue lines show the same for a ...
Factors found to be amplified in human tumors are indicated in green and those found to be frequently lost are indicated in red. Black lines indicate direct activation (arrowheads) or inhibition (bars ...
Figure a shows the eight different geometries designed in this study and the optimization of 3D printing and heat treatment processes to create high-density dislocation defects. Figure b illustrates ...