NAEs are lipid-based endogenous signaling molecules that are produced by combining long-chain fatty acids with ethanolamine. Collectively, NAEs include both endocannabinoids and structurally related ...

Can eating fat be good for us? Some fatty acid molecules actually play a crucial role in maintaining our health and cellular functions. By the early twentieth century, scientists and doctors widely ...

Scientists at Arc Institute and Stanford University have discovered that age-related memory loss may be driven by changes in the gut rather than the brain itself. In a study published in Nature, ...

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in ...

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

(a) Disease progression can be classified into three states: the normal stage, pre-disease stage and disease stage, with the pre-disease stage representing a critical threshold just before the onset ...

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis ...