The cGAS-STING signaling pathway has emerged as a major focus in cancer immunotherapy because it stimulates interferon production and enhances antitumor immune responses. However, despite strong ...
Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer. This pathway, which plays a key role in ...
Researchers have been exploring ways to activate the cGAS/STING pathway in tumors as a way to slow their growth.
(A) Schematic illustration of the generation of C57/6J mice model of cholestasis. The experimental procedure for investigating the protective role of C170 in mice administered a 0.1% DDC diet at week ...
The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...
A protein called STING, previously shown to control a pathway that contributes to antiviral signaling, also plays an important role in cellular stress clearance and cell survival, according to a new ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results