A natural brain defense mechanism shows promise against Alzheimer’s damage, revealing a surprising path scientists are ...

Alzheimer's disease and many other forms of neurodegeneration share a common culprit. In these diseases, tau proteins that ...

A study showed that SORLA protects against toxic tau tangles by reducing tau accumulation, preserving synapses, and limiting ...

Alzheimer's disease and many other forms of neurodegeneration share a common culprit. In these diseases, tau proteins that ...

A protein called SORLA may act as a powerful defense against the toxic tau tangles involved in Alzheimer’s disease. Mice with extra SORLA had less tau accumulation, less brain atrophy, and healthier ...

A mechanism has been found that controls cellular levels of tau, a protein whose abnormal accumulation is at the root of tauopathies, a class of devastating neurodegenerative diseases. The discovery ...

Under normal circumstances, tau protein is part of the brain’s infrastructure, important for stabilizing neurons into their proper shapes. But sometimes tau gets knotted up into tangles and turns ...

The first synthetic fragment of tau protein has been created, revealing more about the diagnosis and treatment of neurodegenerative diseases. Researchers at Northwestern University (IL, USA) and the ...

Research in tauopathies and frontotemporal lobar degeneration got two funding injections this month. The first is a newly established prize for tauopathy research, called the Rainwater Prize Program.

Tauopathies constitute a heterogeneous group of neurodegenerative disorders characterised by the pathological aggregation of tau protein, a microtubule‐associated protein critical for neuronal ...

Scientists studying the non-Alzheimer’s disease tauopathies have struggled to find tracers that will bind the particular forms of tau that predominate in those diseases. At Tau2020, held February ...