Long-acting antiviral medications are transforming HIV prevention and care, requiring only minimalistic dosing. But as the use of lenacapavir expands, scientists are probing a critical question: If ...

A recent study confirms lenacapavir's effectiveness against HIV and highlights the capsid as a promising drug target despite resistance.

A large international clinical trial has unveiled a promising new option for people living with highly treatment-resistant HIV.

A phase 3 clinical trial, led by Professor Chloe Orkin of Queen Mary University of London, has shown that a new, daily oral tablet that combines two current HIV treatment medications – bictegravir and ...

Human immunodeficiency virus (HIV) is a virus that attacks the immune system and weakens the body’s ability to fight off infection. If left untreated, the disease can progress to acquired ...

Salk Institute researchers, in collaboration with National Institutes of Health (NIH) scientists, have discovered the molecular mechanisms by which human immunodeficiency virus (HIV) becomes resistant ...

During a test drive, the mobile lab van uncovered a drug-resistant HIV strain that sprung up after the ongoing war with Russia started.

The mechanism behind how HIV can develop resistance to a widely-prescribed group of drugs has been uncovered by new research, with the findings opening the door to the development of more effective ...

HIV-1 protease is a critical enzyme in the viral life cycle, facilitating the maturation of infectious viral particles by cleaving precursor polyproteins. The emergence of drug resistance, driven by ...

Peter L. Salgo, MD: Individualizing care, individualizing any patient’s regimen, starts with what? How do you identify who needs this? How do you identify how urgent this is? Is it the HIV RNA level, ...

Researchers from the U.S. National Institutes of Health and collaborators recently conducted a study investigating the mechanisms of HIV-1 resistance to integrase strand transfer inhibitors (INSTIs), ...

Researchers who created the first map of human resistance to HIV say their achievement could lead to improved treatments for the virus, which causes AIDS. When a person is infected with HIV, the ...