San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers' season finale versus the Arizona ...

San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury ...

San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

Rookie running back Isaac Guerendo was carted off the field early in the 49ers’ season finale in Arizona against the Cardinals with a leg injury.

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the ...

As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.

The 49ers have been without Isaac Guerendo for most of December. But the RB helped provide a promising update Thursday.

Isaac Guerendo, RB, SF (foot/hamstring) — Expected to play In Guerendo’s Week 16 absence, Patrick Taylor had eight carries for 24 yards, while WR Deebo Samuel had five carries for 25 yards. But ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...

There are numerous player prop betting options on Isaac Guerendo for the 8:15 PM ET game Monday, which airs live on ABC/ESPN.

The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started ...