Multiple people were detained by U.S. Immigration and Customs Enforcement agents in downtown San Francisco on Tuesday morning, merely 12 hours after thousands of protesters took to the streets in the Mission to rally against the widespread raids taking place across California.

Protests erupted nationwide, including in San Francisco, Chicago and NYC, after tensions escalated in LA over immigration raids. See the photos.

Hundreds marched again in San Francisco to protest the ongoing ICE raids in California, the second day of largely peaceful protests marred by incidents of violence and arrests.

Mayor Daniel Lurie, who won on a promise to get tough on crime, is being put to the test in the liberal city—where a peaceful night turned destructive.

San Francisco police arrested 154 people Sunday night after a downtown protest against U.S. Immigration and Customs Enforcement reportedly escalated with the arrival of law enforcement in riot gear.