Programmable CRISPR platform can reduce stem cell differentiation from months to weeks

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, has published new research in ...
ucdavis.edu

Outside-In Signaling Shows a Route Into Cancer Cells

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...
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Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells

Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription ...
JSTOR Daily

Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins

This is a preview. Log in through your library . Abstract Cholesterol-laden macrophage foam cells are a hallmark of atherosclerosis. For that reason, cholesterol metabolism in macrophages has ...

Programming cells: New RNA tool enhances precision in synthetic genetic circuits

Researchers have successfully developed a modular synthetic translational coupling element (SynTCE), significantly enhancing ...
JSTOR Daily

Early programming of CD8⁺ T cell response by the orphan nuclear receptor NR4A3

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 39 (September 29, 2020), pp. 24392-24402 (11 pages) Enhancing long-term persistence while simultaneously ...