Programmable CRISPR platform can reduce stem cell differentiation from months to weeks

Syntax Bio, a synthetic biology company programming the next generation of cell therapies, has published new research in ...
JSTOR Daily

Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins

This is a preview. Log in through your library . Abstract Cholesterol-laden macrophage foam cells are a hallmark of atherosclerosis. For that reason, cholesterol metabolism in macrophages has ...
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Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells

Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription ...
ucdavis.edu

Outside-In Signaling Shows a Route Into Cancer Cells

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Programming cells: New RNA tool enhances precision in synthetic genetic circuits

Researchers have successfully developed a modular synthetic translational coupling element (SynTCE), significantly enhancing ...
JSTOR Daily

Early programming of CD8⁺ T cell response by the orphan nuclear receptor NR4A3

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 39 (September 29, 2020), pp. 24392-24402 (11 pages) Enhancing long-term persistence while simultaneously ...