The race for early cancer detection is one that physicians have been running for millennia. In one of humanity’s oldest surviving medical texts, the ancient Egyptian physician Imhotep described 46 ...

Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...

Readouts of the full DNA of children with cancer at diagnosis have been implemented as the standard of care in a European first. By determining a child's type of cancer as precisely as possible, the ...

Researchers have captured detailed structural images of a DNA repair process called single-strand annealing, identifying a previously unseen intermediate stage. The study, using a yeast protein ...

Newark, Maciej Jeziorek has already accomplished what many scientists take years to achieve: He has coauthored eight ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

PacBio has partnered with Covaris to launch a workflow enabling high-quality HiFi long-read sequencing from FFPE tumor samples, overcoming long-standing DNA damage challenges. The technology could ...

An image of how slide-DNA-seq "sees" cells' organization within a tumor. Credit : Zhao T, Chiang Z, et al. Nature, 2021 Within complex tissues such as cancer tumors, individual cells can vary widely ...