During cell division, adherent animal cells round up to create the precise spatial geometry required for accurate chromosome segregation, a process that depends on the coordinated remodeling of the ...

The Dere Lab is actively working on understanding and evaluating the crosstalk between tumor suppressors lost as part of chromosome 3p deletion associated with renal cell carcinoma (RCC). Clear cell ...

Mitotic segregation of chromosomes depends on correct assembly of the bipolar spindle and mitosis is delayed by the spindle assembly checkpoint (SAC). In the July 19 Nature, Gachet et al., at the ...

Researchers from Nagoya University demonstrated gene bypass events for mitosis using evolutionary repair experiments. They found a novel connection between genes involved in mitosis and glucose ...