Researchers are investigating whether the drug could be used in mainstream medicine—with and without its hallucinatory ...

From ketamine drips to microdosing on LSD, psychedelics are shaking up the way we approach and treat mental health. A growing body of scientific evidence shows that these long-stigmatized substances ...

Researchers from UZH have discovered how the perception of meaning changes in the brain under the influence of LSD. The serotonin 2A receptors are responsible for altered perception. This finding will ...

This article was originally published on Psychedelic Spotlight and appears here with permission. New study suggests that a non-hallucinogenic LSD analog may hold therapeutic potential for mood ...

Researchers at the Icahn School of Medicine at Mount Sinai have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to ...

Classical psychedelics act on a surprisingly broad range of brain receptors, not just the serotonin receptor long associated with their hallucinogenic effects, according to new research published in ...

Psychotropic drugs are all the rage now as a potential treatment of brain diseases. Examples are ketamine and psilocybin for depression and PTSD. More recently, a single dose of LSD was found to have ...

We are rutted in a deepening mental health crisis that is shortening our lifespans and undercutting the economy. The World Health Organization estimates that incidence of conditions such as depression ...

A recent study published in the British Journal of Pharmacology looked into how psychedelics like LSD can affect the biological endocannabinoid system, otherwise targeted by cannabis compounds, which ...

LSD was first synthesized by Swiss chemist Albert Hofmann in 1938. He discovered its powerful psychoactive effects in 1943 after accidentally ingesting a small amount and experiencing vivid ...

Source: By IndependentOo, Dominik from Germany, Maximilian IV, Laitche, NASA; composite artwork by Belbury - CC BY 4.0, Wikimedia Working in his lab at the pharmaceutical company Sandoz in 1938, ...