The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

This work systematically elucidated how the ceramide-FPR2 signaling axis regulates adipocyte ... As a central molecule in the sphingomyelin metabolic pathway, ceramide is closely associated ...

As a central molecule in the sphingomyelin metabolic pathway, ceramide is closely associated with metabolic disorders such as diabetes, obesity, and atherosclerosis. Current research has revealed its ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

The study reveals how ER-stressed adipocytes remotely regulate UPR activation in hepatocytes through the secretion of ceramide ... signaling molecules capable of activating the UPR pathway ...

The study reveals how ER-stressed adipocytes remotely regulate UPR activation in hepatocytes through the secretion of ceramide (Cer ... adipocytes secrete bioactive signaling molecules capable of ...