The Golgi apparatus transports and modifies proteins in eukaryotic cells. How have scientists studied dynamic protein movements through the Golgi? One of the principal observations by Rothman's ...

The hormones insulin and erythropoietin (EPO) are both examples of vesicular proteins. The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous ...

In this project, Oberholtzer found that this sulfhydration process, in modifying a protein called Prdx4 within the Golgi apparatus, confers protection in an oxidative setting. "When you have the ...

It was the early 2000s, and Mukherjee was working in Dennis Shields’s lab at Albert Einstein College of Medicine, studying how cells organize the internal transport of proteins and other cargo. She ...

Another of STING's main functions is regulating the acidity within the Golgi apparatus, a structure within cells that ...

Another of STING's main functions is regulating the acidity within the Golgi apparatus, a structure within cells that processes, packages, and transports proteins and lipids in the body.

Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...