Drug-induced mitochondrial dysfunction has been linked to compound attrition, organ toxicity, black-box warnings and market ...

In 2000, the type 2 diabetes drug Rezulin was withdrawn from the market after several dozen patients required a liver transplant or died due to liver failure. While the vast majority of drugs that ...

Researchers have developed a novel multi-organ-on-a-chip that can demonstrate toxicity more accurately than standard methods. Current drug testing practices have resulted in a large number of drugs ...

Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...

“There had to be some truth to what [drug companies] were selling . . . but in terms of safety, let alone efficacy, that wasn’t part of the equation.” That all changed in 1938, after the deaths linked ...

THUNDER BAY, ON, Feb. 28, 2025 /CNW/ - The illegal toxic drug supply and overdose crisis is having tragic impacts on communities throughout Canada. Our family, friends and neighbours have been ...