Drug-induced mitochondrial dysfunction has been linked to compound attrition, organ toxicity, black-box warnings and market withdrawals, therefore it is important to identify mitochondrial toxicity ...

In 2000, the type 2 diabetes drug Rezulin was withdrawn from the market after several dozen patients required a liver transplant or died due to liver failure. While the vast majority of drugs that ...

Researchers have developed a novel multi-organ-on-a-chip that can demonstrate toxicity more accurately than standard methods. Current drug testing practices have resulted in a large number of drugs ...