An international collaboration has published groundbreaking research, shedding light on the most significant increase in complexity in the history of life's evolution on Earth: the origin of the ...

Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

It is important to recognize Kidney Cancer Awareness Month as a time to get involved, as more than 600,000 people in the U.S. live with kidney cancer. Looking back on March 2025, it is important to ...

INVESTIGATORS AND CLINICIANS anticipate that the next wave of therapeutic approaches in renal cell carcinoma (RCC) will target hypoxia-inducible factor-2 (HIF-2), a transcription factor that is ...

In addition to morphologic resemblance, sporadic urothelial cell ... carcinoma were verified and confirmed by review of pathology reports or medical reports. After written informed consent, histology ...

Localised renal cell carcinoma (RCC) is usually treated surgically, with post-operative imaging-based surveillance to monitor for recurrence. However, surveillance practices vary widely, and patients ...

When these cells were transplanted into the kidneys of AKI mouse models induced by an anti-cancer drug, cisplatin, the animals' survival was vastly improved by preventing the deterioration of ...

Casdatifan, a novel HIF-2α inhibitor, demonstrated a 30% response rate in early trials for metastatic clear cell RCC. ctDNA is gaining attention for its potential role in personalized kidney cancer ...

Squamous cell cancer (SCC) is a type of skin cancer. To determine the severity of SCC, doctors use a staging system. There are five stages in total, ranging from 0 to 4. SCC stages describe the ...

The data come from an international study called AUR87A, which followed patients with clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer. This disease subtype accounts for ...

The team noted that there were 1,425 cases of kidney cancer, or renal cell carcinoma (RCC), among the study's participants, with 583 having aggressive RCC and 339 having fatal RCC. The researchers ...