Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

San Francisco 49ers safety Talanoa Hufanga was a full participant in practice for the first time since tearing a ligament in ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

Christian McCaffrey's stint on the IR might go further than four weeks but the San Francisco 49ers running back could explore ...

Head coach Kyle Shanahan discussed running San Francisco's offense without RB Christian McCaffrey and WR Deebo Samuel Sr., ...

San Francisco 49ers running back Christian McCaffrey has been placed on the injured reserve, but could miss more time after, ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

San Francisco 49ers head coach Kyle Shanahan reveals different preparations against the Los Angeles Rams without Aaron Donald ...

Deebo Samuel believes that the San Francisco 49ers can still become Super Bowl champions, despite his calf injury combined with the absence of Christian McCaffrey leaving the team ...

DL Nick Bosa, WR Brandon Aiyuk and LB Fred Warner shared the team's mindset heading into the 2024 season, discussed the ...