Neither will be eliminated from playoff contention with a loss, but it would be devastating for their 2024 playoff chances.

Getting hurt the Sunday before a Thursday night game gave San Francisco 49ers fans plenty of reason to be skeptical about ...

The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

Most starters were on the sideline late in Week 14's lopsided win, while only one D-lineman played over 30 snaps.

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

It's the fantasy football playoffs, so you know it's no time to mess around. And what we've got with Isaac Guerendo is some ...

Guerendo (foot) is listed as active Thursday against the Rams, Lindsey Pallares of the 49ers' official site reports. Guerendo came out of this past Sunday's win versus the Bears with a sprained foot, ...

According to ESPN's Adam Schefter, San Francisco 49ers rookie running back Isaac Guerendo is expected to suit up for Thursday ...

Is Isaac Guerendo playing on "Thursday Night Football" or is he out? Is Isaac Guerendo injured or healthy for Week 15 TNF?

“49ers rookie RB Isaac Guerendo plans to play Thursday night vs. the Rams despite his sprained foot that has left him being ...