Lionel Messi will miss Inter Miami's crucial Leagues Cup match against Pumas UNAM due to a muscle issue, coach Javier Mascherano said Tuesday.Inter Miami likely need a victory over Pumas in their group stage finale to reach the quarter-finals of the Leagues Cup,

Lionel Messi was on a generational run with Inter Miami, dominating both MLS and the League’s Cup. But in the second match against Necaxa, everything changed as Messi picked up an injury and left the field just 11 minutes into the game.

Maximiliano Falcón saw his one-match ban overturned and will be available to feature in the heart of defense. Federico Redondo is the favorite to enter the lineup instead of Messi, forming a double pivot with Sergio Busquets, allowing Rodrigo De Paul to play in a more advanced role.