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Like Viagra, Tadalafil is a PDE-5 inhibitor. It blocks an enzyme called phosphodiesterase-5 and relaxes the smooth muscle cells in the penis, increasing the blood flow to the organ.

Raynaud’s phenomenon (RP) with or without digital ulcer formation is a significant cause of morbidity for patients with systemic sclerosis (SSc, scleroderma). Lichtenstein reported oral sildenafil as ...

Erectile dysfunction (ED), or impotence, is the inability to achieve and maintain an erection for sexual activity. While the occasional failure to get an erection is not uncommon, if it happens ...