In an interview on the podcast Happy Sad Confused, actress Margaret Qualley shared that the prosthetics she wore for the movie "The Substance" caused her face to break out in "absurd" acne.

Margaret Qualley says her skin went through a lot while filming 'The Substance.' On Josh Horowitz’s 'Happy Sad Confused' podcast, the actress opened up about the effects of wearing prosthetics for the film and how it impacted her skin.

Margaret Qualley shares the challenges of The Substance, a role that pushed her limits and earned acclaim. These actors never use their real accent. For this list, we’ll be looking at, and listening to actors whose accent we hear most on screen isn’t the one they use in their real lives.

While Margaret Qualley has garnered high praise for her performance in 2024’s The Substance, she has revealed that the extensive amount of prosthetics that were required for the film took a toll on her skin.

The Substance is a fictional horror movie, however, some of its transformations turned out to be very real, and even semi-permanent, according to one of its star Margaret Qualley. The actor recently spoke about her prosthetics for the film in an episode of Josh Horowitz’s Happy Sad Confused podcast and revealed that her face suffered so much that it could no longer be seen on camera.

In 'The Substance,' Margaret Qualley wore a mountain of facial prosthetics, which had a detrimental effect on her face.