Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Mitochondria produce energy-rich molecules known as ATP, which power everything we do. But mitochondria are picky: they need a specific molecule called pyruvate, created from sugars, to make the ...

Scientists have cracked the structure of the mitochondrial pyruvate carrier, a fuel gate inside our cells, after 50 years of speculation. The discovery could revolutionize treatment strategies for ...

Using cryo-electron microscopy, the team uncovered the structure and function of the mitochondrial pyruvate carrier at the atomic scale. This carrier transports pyruvate, a byproduct of sugar ...