Yet on Sunday night in frigid Orchard Park, the 49ers, mired at 5-6 and a game out of first place in the NFC West, find their ...

Josh Allen is currently the frontrunner in NFL MVP odds, and we expect the Bills superstar quarterback to use his athleticism ...

The Buffalo Bills will host the San Francisco 49ers at Highmark Stadium on “Sunday ... the team will have plenty of options ...

Three things I’m pondering as the Bills return from their bye for the stretch run… Mila-No More Waiting Matt Milano is ...

It's Week 13, and the San Francisco 49ers are at 5-6 in the season. The team travels to Buffalo to take on the leaders of the ...

With no teams on a bye, Week 13 Fantasy football lineups are more stacked than previous weeks. Who you deploy as part of your ...

There are no fewer than 20 running backs who could finish the season as 1,000-yard rushers, with Saquon Barkley carrying the ...

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

Running back Christian McCaffrey says the San Francisco 49ers are “hungry” to make a playoff push even with the defending NFC ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

But even when most or all of those Niners took the field this year, closing out games has been a glaring weakness for a team expected to compete for the NFC. A loss to Seattle in Week 11 marked the ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...