Boehringer Ingelheim’s Spevigo (spesolimab) has been recommended by the National Institute for Health and Care Excellence (NICE) to treat generalised pustular psoriasis (GPP) flares.

the Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) total score is 3 or more (at least moderate), and there are new or worsened pustules, and the GPPGA pustulation subscore is at ...

Evidence-based recommendations on spesolimab (Spevigo) for treating generalised pustular psoriasis flares in adults. Last reviewed: 18 June 2025 Next review: This guidance will be reviewed if there is ...

A 54-year-old woman with well-controlled chronic plaque psoriasis presented with a 2-day history of painful rash and fever. Widespread erythematous patches with overlying, coalescing pustules were ...

German drugmaker Boehringer Ingelheim has its first regulatory approval for spesolimab, its antibody therapy for rare and life-threatening skin disorder generalised pustular psoriasis (GPP), in ...

Pepople in England and Wales with a rare and severe form of psoriasis are celebrating the news that they may soon be able to access a new, first-in-class treatment from Boehringer Ingelheim. NHS ...

A rare case of adalimumab-induced pustular psoriasis in a hidradenitis suppurativa patient was successfully treated with ...

Psoriasis reacts differently for each person. You could find that particular behaviors or situations cause your psoriasis to flare, even for something that’s not well recognized as a trigger.

Pustular psoriasis, lacking spongiform pustules, can also mimic SPD histologically. [4] Reports commonly link SPD to monoclonal gammopathies (usually IgA), and multiple myeloma. [5] ...

Certain psoriasis medications, such as immunosuppressants and biologics, may also have this effect. For this reason, it’s important to support your immune system.