The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

Most starters were on the sideline late in Week 14's lopsided win, while only one D-lineman played over 30 snaps.

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

Getting hurt the Sunday before a Thursday night game gave San Francisco 49ers fans plenty of reason to be skeptical about ...

Neither will be eliminated from playoff contention with a loss, but it would be devastating for their 2024 playoff chances.

ESPN’s Adam Schefter reports that San Francisco 49ers running back Isaac Guerendo plans to play through the injury against ...

Guerendo (foot) is listed as active Thursday against the Rams, Lindsey Pallares of the 49ers' official site reports. Guerendo came out of this past Sunday's win versus the Bears with a sprained foot, ...

Is Isaac Guerendo playing on "Thursday Night Football" or is he out? Is Isaac Guerendo injured or healthy for Week 15 TNF?

If the San Francisco 49ers want to defend their NFC West title, they must defeat the Los Angeles Rams in Week 15. However, the team enters Thursday Night Footba ...

The 49ers will have defensive lineman Nick Bosa, linebacker Dre Greenlaw and running back Isaac Guerendo for Thursday Night Football.

Good news for the 49ers. Rookie running back Isaac Guerendo is expected to play through a foot sprain tonight against the Los Angeles Rams, according to ESPN's ...