Most starters were on the sideline late in Week 14's lopsided win, while only one D-lineman played over 30 snaps.

PM ET game airing live on Amazon Prime Video, bookmakers have posted player props for Isaac Guerendo. NFC West rivals play in ...

Linebacker Dre Greenlaw is cleared to suit up again for the 49ers tonight, 10 months after tearing his left Achilles in the ...

Getting hurt the Sunday before a Thursday night game gave San Francisco 49ers fans plenty of reason to be skeptical about ...

Micah Roberts, on a 26-6 run on 49ers picks, has revealed his Week 15 Thursday Night Football expert picks for Los Angeles vs ...

If the San Francisco 49ers want to defend their NFC West title, they must defeat the Los Angeles Rams in Week 15. However, the team enters Thursday Night Footba ...

San Francisco 49ers linebacker Dre Greenlaw and defensive lineman Nick Bosa are set to make their return from injury versus ...

During the divisional rivalry game between the San Francisco 49ers and the Los Angeles Rams, Isaac Guerendo took a handoff ...

Running back Isaac Guerendo is officially active for the the 49ers' pivotal "Thursday Night Football" game against the Los Angeles Rams despite dealing with a foot injury on a short week.

The San Francisco 49ers are about an hour and a half away from taking on the Los Angeles Rams, and the inactive list is out.

For the first time maybe all season, the San Francisco 49ers are getting good news when it comes to injuries and inactive for ...

San Francisco 49ers QB Brock Purdy, LB Fred Warner, TE George Kittle, DL Nick Bosa and LB Dre Greenlaw outlined the team's ...