The EMBO Journal5d
Hair follicle stem cells and the collapse of self-tolerance in alopecia: the interplay of barrier function, the microbiome, and immunity
The hair follicle is a dynamic miniature organ. Its permanent portion opens to the skin surface, communicates with sebaceous ...
The EMBO Journal10d
Rett syndrome: interferon-γ to the rescue?
In conclusion, this intriguing report builds on the work of many other groups by further unraveling MECP2 function in the ...
The EMBO Journal3d
The winter holidays are glorious—except when they’re not
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal13d
TRPC5: a new entry to the chromaffin cell’s palette of ion channels that control adrenal response to hypoglycemia
Hypoglycemia is an extremely common side effect of insulin therapy experienced mainly by patients with type 1 diabetes ...
The EMBO Journal9d
Making contact away from home: a bacterial secreted effector mediates inter-organelle communication
Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...
The EMBO Journal3d
Nuclear receptor E75/NR1D2 promotes tumor malignant transformation by integrating Hippo and Notch pathways
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Hormone therapy resistance and the ensuing ...
The EMBO Journal4d
Circadian rhythms of macrophages are altered by the acidic tumor microenvironment
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Tumor-associated macrophages (TAMs) are prime ...
The EMBO Journal17d
Deep quantification of substrate turnover defines protease subsite cooperativity
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Substrate specificity determines protease ...
The EMBO Journal3d
PTGS is dispensable for the initiation of epigenetic silencing of an active transposon in Arabidopsis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. PTGS facilitates but is not required for the ...
The EMBO Journal6d
Structural basis of 3′-tRNA maturation by the human mitochondrial RNase Z complex
a Gold-standard 0.143 FSC resolution calculated with 3DFSC (Tan et al, 2017). The masks for FSC calculation were generated in CryoSPARC using a relative threshold of 0.5. b Gold-standard 0.143 FSC ...
The EMBO Journal5d
Glutamine sensing licenses cholesterol synthesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...