In nearly all of the cases, FXS is caused by an expansion of an untranslated CGG repeat in the 59-untranslated region of the X-linked gene fragile mental retardation 1 (FMR1; Verkerk et al., …

Abstract Memories are much more easily impaired than improved. Dementias, a lasting impairment of memory function, occur in a variety of cognitive dis-orders and become more …

The macrocyclic lactone bryostatin, a natural product extracted from Bugula neritina, was found to activate PKC isozymes selectively (Etcheberrigaray et al., 2004). These PKC isozymes then …

There is strong evidence that protein kinase C (PKC) isozyme signaling pathways are causally involved in associative memory storage. Other observations have indicated that PKC signaling …

Neurotrope Submits an Amended Protocol to the U.S. Food and Drug Administration for its Phase 2b Clinical Trial of its Lead Drug Candidate, Bryostatin-1, for the Treatment of Advanced …

Synaptogenix | Press Release 261 archive,category,category-press-release,category-261,ajax_fade,page_not_loaded,,select-theme-ver-4.4,smooth_scroll,wpb-js-composer js …

A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Assessing Safety, Tolerability, and of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer’s Disease Martin …

Introduction Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by insidious cognitive decline and memory dysfunction [1]. Synapse loss is the best …

Personal data is information that specifically identifies an individual, such as an address, telephone number, e-mail address, and information about that individual’s activities when …

Adduct formation in liquid chromatography-triple quadrupole mass spectrometric measurement of bryostatin 1