Feb 3, 2022 · By definition, eigengenes are the right singular vectors of the SVD of the expression matrix (row as genes, column as samples). This concept become popular when WGCNA used …

Nov 21, 2007 · Eigengene networks can be effective and biologically meaningful tools for studying the relationships between modules of a gene co-expression network. The proposed methods …

Dec 22, 2024 · Explore module eigengenes and their role in gene expression, uncovering hidden relationships and insights in biological data. Discover the colours of genes!

Sep 23, 2025 · We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘ eigengenes ’’/‘‘eigenarrays’’ space, where the …

Module eigengenes in a dataframe, with each column corresponding to one eigengene. The columns are named by the corresponding color with an "ME" prepended, e.g., MEturquoise etc.

Module eigengenes (MEs) are defined as the first principal component of the expression matrix of the corresponding module and reflect a general expression level of the genes in that module ...

eigengene (pl. eigengenes) (genetics) (mathematics) One of a set of right singular vectors of a genes x samples matrix that tabulates, e.g., the mRNA or gene expression of the genes …

May 13, 2024 · To our knowledge, this is the first study to explore the genetic and environmental contributions to weighted gene co-expression network analysis module eigengenes (MEs).

Jun 18, 2025 · We describe the use of singular value decomposition in transforming gene expression data from genes/arrays space to ‘‘eigengenes’’/‘‘eigenarrays’’ space, where the …

Nov 21, 2007 · We represent the gene expression profiles of each module by an eigengene. Second, we propose a method for constructing an eigengene network, where the edges are …