CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol (GPI) tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 …

The cell surface antigen CD14 is primarily understood to act as a co-receptor for toll-like receptors (TLRs) to activate innate immunity responses to pathogens and tissue injury in macrophages and …

Nov 13, 2025 · Complete information for CD14 gene (Protein Coding), CD14 Molecule, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene …

Jan 9, 2026 · Multiomic analyses (RNA-seq, proteomics, flow cytometry) of neutrophils at 3-hour following DVT revealed consistent overexpression of CD14. Neutrophil-specific CD14 knockdown …

Feb 25, 2023 · Consistent with these broader functions, CD14 expression is altered in a variety of non-immune cell types in response to a several of disease states. Moreover, soluble CD14 activated by …

Jun 28, 2025 · CD14 positive cells are a group of immune cells identified by the CD14 protein on their surface. These cells act as sentinels, forming a part of the body’s initial defense mechanisms against …

CD14 CD14 is a lipopolysaccharide-binding protein, which functions as an endotoxin receptor. It is anchored to the cell surface by linkage to GPI. CD14 is strongly positive in monocytes and most …

Sep 24, 2024 · Our findings propose CD14 as a crucial chaperone of Fas receptor internalization in macrophages and neutrophils, resulting in Cd14−/− myeloid cells that are protected from FasL …

Mar 3, 2023 · The cell surface antigen CD14 is primarily understood to act as a co-receptor for toll-like receptors (TLRs) to activate innate immunity responses to pathogens and tissue injury in …

CD14 protein expression summary - The Human Protein Atlas CD14 () protein expression summary.