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Sjogren's
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0:57
YouTube
MedLecturesMadeEasy
Sjogren syndrome
Pathogenesis: Immune-mediated destruction of lacrimal/salivary glands Can be primary disease or secondary with other AI (SLE, RA) Exocrine features: Keratoconjunctivitis sicca Dry mouth, salivary hypertrophy Xerosis of skin Extraglandular features: Raynaud phenomenon Cutaneous vasculitis Arthralgia/arthritis Interstitial lung disease ...
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